5 Best Ergonomic Gaming Mice

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Penned by Kody Wirth

Kody is our expert Destiny 2 and shooter genre writer. He lives in Oregon.

Reviewed by Benjamin Barr

If you spend long hours in front of a computer, you’ve likely experienced some level of joint pain. While you may immediately jump to researching ergonomic gaming chairs and convertible desks, it may make more sense to focus on a peripheral you use just as often — your mouse. This article points you towards the best ergonomic gaming mice on the market. But first, a look at why they’re so important.

Why Use an Ergonomic Gaming Mouse?

Like most computer and office equipment, the standard mouse (e.g., the one that came with your prebuilt computer) is not designed for comfort. Instead, manufacturers develop them to function for as cheap a cost as possible.

While gaming mice take things a step further with lighter, sleeker, multi-button designs, that hardly enough. The issue here is that gaming mice are developed with performance in mind, and often sacrifice forearm, wrist, palm, and finger comfort to squeeze out a few more clicks. That’s not to say that every gaming mouse is designed without ergonomics. Some — especially those from top brands — help you avoid long-term pain and medical issues while retaining top-tier performance.

If you’ve been experiencing any physical pain while using your PC, instead of shelling out big bucks for a standing desk, why not start smaller with an ergonomic gaming mouse and see how you feel.

Zoom In: The 5 Best Ergonomic Gaming Mice

To help you cut to the chase, we’ve compiled the top 5 ergonomic mice designed with PC gaming in mind.

1. Razer DeathAdder V2

The best ergonomic mouse for gaming

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Brand: Razer | DPI: 20,000 | Ergonomic Style: Right-Handed | Buttons: 6 | Weight: 2.9 oz | Price: 💰

There’s a reason that Razer has left each iteration of the DeathAdder’s shell design relatively untouched. Why mess with perfection? 

The DeathAdder is incredibly comfortable for claw, palm, and finger grip, thanks to the right-handed ergonomic design. And it doesn’t stop at comfort. 

Thanks to the Focus+ optical sensor, PTFE mouse feet, and lighter shell, you’ll be able to perform lightning-fast movements with incredible accuracy. Moreover, you’ll never miss a button press thanks to the two generously sized thumb switches located just above the rubberized lower grip.

The DeathAdder is the ideal choice for those venturing into the world of ergonomic gaming mice. It’s versatile and built to last, no matter your play style. Thankfully, it’s also available at a reasonably low price, meaning you won’t break the bank for high-level comfort and performance.

2. Corsair Ironclaw

The best XL size ergonomic gaming mouse

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Brand: Corsair | DPI: 18,000 | Ergonomic Style: Right-Handed | Buttons: 7 | Weight: 3.7 oz | Price: 💰

Corsair has made plenty of attempts to develop a well-rounded ergonomic mouse over the years. Typically it’s the use of cheaper plastics that reviewers and consumers find to be an issue. But that isn’t the case with the Ironclaw. 

Rather than creating a shell out of a single material, each panel, button, and switch is made with a unique grip or plastic coating. Combine that with the contoured shape, pronounced arch, and lower left-hand lip, and you have a well-balanced ergonomic mouse for palm and claw styles.

Designed for those with larger hands, the Ironclaw isn’t afraid to throw its weight around. No, really — this mouse feels beefy! But it balances this heft with precise surface calibration, customizable in one DPI increments, to keep movements snappy and responsive. 

The only drawback here is Corsairs’ history of so-so quality. Their proprietary iCUE software is a comprehensive but messy customization system, and for some customers, the buttons, switches, and scroll wheel have all been known to break after a few months. Overall, the Ironclaw is a well-designed extra-large ergonomic option, but you’ll need to be ok with a potentially short lifespan.

3. Razer Viper Ultimate

The best ergonomic wireless mouse

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Brand: Razer | DPI: 20,000 | Ergonomic Style: Ambidextrous | Buttons: 8 | Weight: 2.4 oz | Price: 💰💰💰

Almost all of Razer’s gaming mice are reliable options. But if you want the best wireless model with ridiculously long battery life, you’ll want to go with the Viper Ultimate. 

Besides having an ambidextrous casing design similar to the DeathAdder, the Viper also mimics its high-performing DPI capabilities. And with a 650 IPS rating, you’ll be able to accurately track rapid movement speeds that would be impressive even for a high-quality wired mouse. Throw Razer’s optical mouse switches into the mix, and you have a truly responsive setup with virtually no latency.

One element that’s both a benefit and a drawback is how lightweight the Viper is. It’s surprisingly weightless and almost glides across the mousepad, only adding to its responsive nature. Unfortunately, that comes at a cost. Most noticeably in the cheap buttons that feel somewhat out of place for such a well-rounded peripheral.

Buttons aside, the Viper performs like a wireless version of the DeathAdder V2. The ergonomic design works wonderfully for multiple grip styles, and the 70+ hour battery plus wired charging option puts it a step above similar wireless models. 

4. Logitech MX Vertical

The best Logitech ergonomic mouse

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Brand: Logitech | DPI: 4,000 | Ergonomic Style: Right-Handed Vertical | Buttons: 4 | Weight: 4.8 oz | Price: 💰💰

While not the best gaming mouse Logitech has to offer, the MX Vertical is their best ergonomic model. Unlike the rest of the mice on this list, it’s a fully ergonomic design meant to combat arthritis and wrist pain. This is done through the vertical shell design, which allows the user’s hand to rest naturally in a neutral position instead of palm-down.

Now, the vertical design does bring with it quite the learning curve. Yes, it is a better layout for you physically, but it won’t be a natural transition. Add in the limited sensitivity range and lesser number of programmable buttons, and you have quite the setup to get used to.

But here’s the thing about the MX: while it may not hit top-level DPI settings or feature top-of-the-line mechanical switches, it makes up for that with consistency. You’ll always feel comfortable playing, your tracking will always be on-point, and you’ll need to make less drastic movements thanks to the vertical layout. Plus, the optional wireless setting retains this accuracy, which is a welcome surprise.

The MX won’t fit the bill for most, that’s true. But if you need something genuinely ergonomic, this is your best bet.

5. Logitech G203

The best budget ergonomic gaming mouse

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Brand: Logitech | DPI: 8,000 | Ergonomic Style: Right-Handed | Buttons: 5 | Weight: 3.0 oz | Price: 💰

Fully committing to an expensive ergonomic mouse isn’t for everyone. Luckily, you can start with a relatively inexpensive option to see how it affects you by purchasing the Logitech G203.

Like most ergonomic gaming mice, the G203 is designed with minimalized comfort elements. Rather than a pronounced vertical shell or thumb grips, it instead leverages a sleek arched casing to provide support. 

Performance-wise it also treads that middle ground with a decently high DPI range, reactive switches, and five programmable buttons that aren’t anything to write home about.

That said, this is the best option for those that don’t know what they want in an ergonomic mouse. It’s inexpensive, features hints of comfort, and still performs well enough to be competitive. You probably won’t stick with this mouse long-term, but it’s worth the purchase for a high-quality test-run.

Buyer’s Guide: Ergonomic Gaming Mice 

Finding the right gaming mouse can be difficult. Throw the need for an ergonomic design into the mix, and it can feel downright impossible. To help narrow down your choices, keep the following points in mind as you look through this list.

1. Ergonomic Design

The whole point of an ergonomic mouse is to alleviate tension and support your hand’s natural positioning. If you go with a model that doesn’t fit your specific needs, you could be doing more harm than good.

Not every mouse fits every grip or hand size. And not every mouse is fully ergonomic. Make sure you know the orientation, the way you like to grip, and any other comfort features you may need to avoid aches and pains. 

2. Size

Similar to the ergonomic function, size can be an equally disastrous issue. If your mouse is too small, you invite the possibility of aggravated wrist pain. If it’s too large, you risk potentially overextending your fingers.

And physical ailments aside, if a mouse doesn’t comfortably fit in your hand, you simply won’t get good use out of it. Rather than honing in on specific settings or adjusting the compatibility to fit your mouse pad, you’ll be too busy dealing with an ill-fitting mouse.

3. Performance

Last on our list? Performance.

You’ll want to be sure that the mouse you choose is up to snuff in competitive scenarios. If it’s from a traditional gaming brand like Logitech, Razer, Corsair, and even Microsoft, you shouldn’t have any problems finding a reliable option. 

But like any peripheral, be sure that the mouse features warrant the price. It can be easy to get caught up in high-level DPI and promises of withstanding several million clicks. These are just vanity metrics, and you’ll want to dig a bit deeper to make sure you’re actually getting a high-performance mouse. 

Our Process

For this guide on ergonomic gaming mice, our writers spent 3 hours researching over 35 of the most popular options from brands big and small. After comparing this data, we then read over 105 user reviews and narrowed our list down to the top 5 ergonomic mice on the market. All of this research adds up to recommendations you can trust.

We hope you’ve found the perfect model for your setup. Happy Gaming!

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